Publications & Patents — Khalid K. Alam, Ph.D.

14 Publications

6 Patent families

1771 Citations

12 h-index

13 i10-index

per Google Scholar, August 25, 2026

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Peer-Reviewed Publications

2024

Developing, Characterizing, and Modeling CRISPR-Based Point-of-Use Pathogen Diagnostics ACS Synthetic Biology Open access

2022

FASTAptameR 2.0: A web tool for combinatorial sequence selections Molecular Therapy - Nucleic Acids Open access
Programming cell-free biosensors with DNA strand displacement circuits Nature Chemical Biology Open access
ROSALIND: Rapid Detection of Chemical Contaminants with In Vitro Transcription Factor-Based Biosensors Link only

2020

2′-Fluoro-Modified Pyrimidines Enhance Affinity of RNA Oligonucleotides to HIV-1 Reverse Transcriptase RNA Link only
Cell-free biosensors for rapid detection of water contaminants Nature Biotechnology Link only
A primer on emerging field-deployable synthetic biology tools for global water quality monitoring npj Clean Water Open access
Design and Optimization of a Cell-Free Atrazine Biosensor ACS Synthetic Biology Link only

2019

Design of a Transcriptional Biosensor for the Portable, On-Demand Detection of Cyanuric Acid ACS Synthetic Biology Link only

2018

Poly-Target Selection Identifies Broad-Spectrum RNA Aptamers Molecular Therapy - Nucleic Acids Open access
Modular cell-internalizing aptamer nanostructure enables targeted delivery of large functional RNAs in cancer cell lines Nature Communications Open access

2017

A Fluorescent Split Aptamer for Visualizing RNA-RNA Assembly In Vivo ACS Synthetic Biology Open access

2016

In Vivo Analysis of Infectivity, Fusogenicity, and Incorporation of a Mutagenic Viral Glycoprotein Library Reveals Determinants for Virus Incorporation Journal of Virology Link only

2015

FASTAptamer: A Bioinformatic Toolkit for High-Throughput Sequence Analysis of Combinatorial Selections Molecular Therapy - Nucleic Acids Open access

Patents

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Analytes' detection using regulated in vitro transcription Family B · issued (active) · US 12,203,144
On demand, portable, cell-free molecular sensing platform Family A · issued (active) · US 12,098,433
Cell-free biosensors with DNA strand displacement circuits (± PSR) Family D · pending
Stabilization and Preservation of In Vitro Transcription Reactions Family C · pending
Detection of Chemicals and Molecules Using Cell-free Biosensor Lateral Flow Assays Family E · Published application
Nucleic Acid Enzyme Biosensors, Kits and Methods Family F · Provisional application